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Four posters about the novel, fixed‐dose calcipotriol and betamethasone dipropionate cream (CAL/BDP cream) based on Poly‐Aphron Dispersion (PAD) Technology were presented at the 30th European Academy of Dermatology and Venereology (EADV) Congress 2021 and are summarized here. CAL/BDP cream was compared in two randomized, phase 3 trials to vehicle and active comparator (CAL/BDP gel/topical suspension...
This article summarizes a presentation titled ‘The role of topical therapies along the psoriasis patient journey’ held at the Satellite Symposium of the 30th European Academy of Dermatology and Venereology Congress. During this session, the role of topical treatments in the management of psoriasis was presented, with a particular focus on the current unmet needs and data gaps. Psoriasis plays a significant...
This article is based on a presentation given by authors at the Satellite Symposium titled ‘Tailoring topical psoriasis treatments to patients' needs and expectations’ held during the 30th European Academy of Dermatology and Venereology Congress. During this session, the factors affecting adherence and outcomes to topical treatments were presented, with a particular focus on the patients' point of...
Background
Acne is a very common condition. Currently, there are relatively few studies available to help guidance‐based decisions for its long‐term management, especially studies with cosmetic care products. We have developed a skin care product dedicated to adult female acne.
Objectives
Evaluate the efficacy and tolerance of the test product containing Myrtus communis extract and azelaic acid...
Introduction
Acne is a multifactorial inflammatory disease of the pilosebaceous unit in which Cutibacterium acnes is one of the main triggers. A strong predominance of C. acnes phylotype IA1 is present in acne skin with higher biofilm organization and virulence, promoting local immuno‐inflammation, especially the Th17 pathway.
Objectives
We evaluated the single and combined pharmacological properties...
Acne vulgaris is a common chronic inflammatory skin disease of the pilosebaceous units. Four factors contribute to acne: hyperseborrhea and dysseborrhea, follicular hyperkeratinisation, skin microbiome dysbiosis and local immuno‐inflammation. Recent key studies have highlighted a better understanding of the important role of Cutibacterium acnes (C. acnes) in the development of acne. Three major findings...
Background
Acne is a multifactorial chronic inflammatory disease of the pilosebaceous unit, where Cutibacterium acnes plays a main role. Recent papers demonstrated that specific C. acnes phylotypes were correlated with the severity of inflammatory acne and reported a specific loss of C. acnes phylotype diversity in this context.
Objectives
The aim of this exploratory study was to evaluate the efficacy...
Introduction
Scars are visible marks from various causes, including surgery, skin injury, burning or dermatological disease, and may impact the quality of life.
Objective
To assess the impact of scars on quality of life (QoL).
Material and Methods
Data about sociodemography, presence, origin, and symptoms of scars were collected using an Internet survey between April and May 2020. Overall, 11,100...
Skin wounds are common and represent a major public health and economical problem, with risks of complications and a significant negative impact on the quality of life of patients. Cutaneous wound healing is a tightly regulated process resulting in the restoration of tissue integrity. Wound healing involves the interaction of several skin, immune and vascular cells, growth factors and cytokines. However,...
A thorough knowledge of non‐surgical procedures (laser, peelings, injections, threads) and surgical procedures (combined surgeries and skin grafts), including contraindications and potential risks and side effects, (e.g. infection, hypopigmentation, hyperpigmentation, and scarring) is essential to be able to reduce their incidence and ensure the patient receives the most benefit from the procedure...
Background
Solar light induces or aggravates hyperpigmentation issues. The contribution of UVA1, as well as visible light (VL), especially high‐energy blue‐violet visible (HEV) light, is now clearly established.
Objectives
This work aimed at determining the relative contribution of UVA1, HEV and VL wavelength bands and their sub‐domains in pigmentation induction.
Methods
Two clinical studies...
A dysfunctional epidermal barrier, which may be associated with mutations in the filaggrin gene in genetically predisposed individuals or harmful effects of environmental agents and allergens, contributes to the development of atopic dermatitis (AD) due to an interplay between the epithelial barrier, immune defence and the cutaneous microbiome. The skin of patients with AD is frequently over‐colonized...
Background
Moderate to severe AD can be successfully managed by systemic treatments. Current guidelines also recommend emollients or emollients ‘plus’ and eudermic cleansers for all AD patients to improve the skin barrier and provide anti‐irritant and anti‐pruritic effects.
Objectives
To investigate the efficacy of skin care (in addition to systemic treatment) with an Emollient ‘plus’ balm designed...
Background
Emollients are the baseline treatment for mild or moderate atopic dermatitis (AD) to improve the epidermal barrier and provide anti‐irritant and anti‐pruritic effects. Emollient ‘plus’ can influence the skin microbiome of atopic eczema patients.
Objectives
To evaluate the benefits of using Emollient ‘plus’ to reduce corticosteroid consumption.
Methods
In an open, single‐centre, randomized,...
Background
Overexposure to sunlight can have many harmful biological effects on the skin, leading to skin cancer and photoaging. As ultraviolet (UV) radiation has been identified as a cause of DNA damage and oxidative stress in the skin, the photoprotection provided by sunscreens is evaluated through their ability to filter UV light, using the sun protection factor (SPF). However, recent data have...
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